Molecular mechanisms linking microbiome and disease in adults and children

2019 – POLLGUT: “Linking environmental pollution and gut microbiota in individuals living in contaminated settlements”, granted by the Italian Ministry of Health

2017 - University-Industry cooperation, PROBE-2: “L. casei DG® (Lactobacillus paracasei CNCMI1572; Enterolactis Plus®) for treatment of patients with Irritable Bowel Syndrome”, granted by SOFAR

2017 - University-Industry cooperation: “Analysis of circulating microRNA in NAFLD patients in response to L. casei DG® (Lactobacillus paracasei CNCMI1572) treatment”, granted by SOFAR

2017 - “Gut microbiota in children with Rett syndrome”, granted by the Associations “ConRett” and “La fabbrica dei sogni 2-New developments for Rett Syndrome”

2016 - Micro-SPES: “Scientific Study Protocol SPES – Campania Trasparente, Integrated Monitoring of Campania Region, within the activity: Evaluation of microbiota composition in individuals living in area with different environmental pollution levels”, granted by Istituto Zooprofilattico Sperimentale del Mezzogiorno

2016 – “Integrating epigenetics, metabolomics and gut microbiota profiles to achieve personalized medicine in heart failure”, granted by Compagnia San Paolo S.p.a. within the Programme STAR

2016 – “Effect of a milk matrix fermented with the probiotic L. paracasei CBAL74 on the immune system of newborns”, granted by the Italian Ministry of Health

2016 - University-Industry cooperation: “Effect of a new formula enriched with a milk matrix fermented by L. paracasei CBA L74 on innate and acquired immunity in newborns”, granted by Kraft-Heinz Company (USA)

2016 - University-Industry cooperation: “Defining the mode of action of an extensively hydrolyzed casein formula enriched with probiotics or postbiotics for prevention and treatment of cow’s milk allergy”, granted by Mead Johnson (USA)

2016 – University-Industry cooperation: “Effect of the probiotic strain Bb12 on infant colic”, granted by Sofar

2015 – “Immune regulation and tolerance in health and disease: the role of Bifidobacteria”, granted by the Italian Ministry of Foreign Affairs within the Programme of Scientific and Technological Cooperation between Italy and South Korea

2014 - University-Industry cooperation: “Epigenetic mechanisms caused by dietary treatment with an extensively hydrolyzed casein formula containing the probiotic strain LGG in children with cow’s milk proteins allergy”, granted by Mead Johnson (USA)

2014 – “Study of the gut microbiome in the adult celiac disease pathogenesis”, granted by Fondazione Celiachia

2013 – “Use of Microorganisms for Carotenoids Delivery: Next Generation of Probiotics for Cardiovascular Disease”, granted by the European Union

2013 - “Microbiota as potential target for innovative preventive and therapeutic strategies for food allergy”, granted by the Italian Ministry of Health

2013 – University-Industry cooperation: “Effect of a dietary treatment with Nutramigen LGG on the risk of atopy in children with cow’s milk proteins allergy”, granted by Mead Johnson (USA)

2013 - University-Industry cooperation: “Effect of Nutramigen LGG on gastrointestinal disorders in children with cow’s milk proteins allergy”, granted by Mead Johnson (USA)

2013 - University-Industry cooperation: “Effect of fermented rice or milk matrices on the risk of infections in children”, granted by Heinz Italia

2013 - University-Industry cooperation: “Defining an animal model of cow’s milk proteins allergy to study the effects of probiotics and postbiotics”, granted by Mead Johnson (USA)

2012 – University-Industry cooperation: “Probiotics in Cystic Fibrosis”, granted by the Cystic Fibrosis Foundation Therapeutics (USA)

 

Diet and microbiome

2019 - H2020-MASTER: “Microbiome Applications for Sustainable food systems through Technologies and EnteRprise”, granted by the European Union within the Horizon2020 Programme

2019 – PRIN2017: “Microbiome-tailored food products based on typical Mediterranean Diet components”, granted by the Italian Ministry of University and Research

2019 – University-Industry cooperation: “Design and development of a bakery product enriched in beneficial nutrients for the gut microbiome”, granted by Fresystem S.p.a.

2018 – JPI HDHL-DiGutMet: “Dissecting diet x gut microbiome interactions determining cardiometabolic risk using molecular phenotyping and development of tailored alteration strategies”, granted by the Italian Ministry of University and Research within the Joint Transnational Call HDHL-INTIMIC “Interrelation of the Intestinal Microbiome, Diet and Health”

2018 - University-Industry cooperation, MedGICarb: “Effectiveness of pasta and other starchy foods with a low glycemic response to reduce the postprandial glucose and insulin response, improve the cardiovascular risk factor profile and promote long-term well-being”, granted by Barilla G.& R. Fratelli S.p.A.

2016 – JPI HDHL-DINAMIC: “Diet-induced Arrangement of the gut Microbiome for improvement of Cardiometabolic health”, granted by the Italian Ministry of University and Research within the Joint Transnational Call “Intestinal Microbiomics”

2013 - PRIN2010/2011-Diet4MicroGut: “Microorganisms in food and humans: microbiota and metabolome in subjects consuming an omnivore, vegetarian or vegan diet”, granted by the Italian Ministry of University and Research

2009 - ETHERPATHS: “Characterization and modelling of dietary effects mediated by gut microbiota on lipid metabolism”, granted by the European Union within the 7th Framework Programme

2005 - HEALTHGRAIN: “Exploiting Bioactivity of European Cereal Grains for Improved Nutrition and Health Benefits”, granted by the European Union within the 7th Framework Programme

 

Gut-brain axis

2016 - PRIN2015: “Biological and pharmacological HDAC inhibitors in a genetic model of epilepsy and in experimental pain models: role of the microbiome and SCFAs”, granted by the Italian Ministry of University and Research